Downs syndrome patients four times more likely to develop type 2 diabetes – Medical Dialogues

A recent study found that young Downs syndrome patients have four times more incidence of type 2 diabetes than controls due to higher body mass index. The study was published in the journal Diabetes Care.
Down syndrome (DS) is the most common form of chromosomal trisomy. The risk of diabetes is increased by the genetic factors in DS. So, researchers conducted a study to determine whether DS is associated with an increased incidence of diabetes and the relationship with obesity across the lifespan compared with control patients. Based on the data from UK Clinical Practice Research Datalink, a population-based cohort study was performed and analyzed from 1990 to 2020.
RESULTS
Thus, the study shows that the incidence of diabetes in patients with DS is higher and at a younger age than controls due to higher BMI.
Aisha A. Aslam, R. Asaad Baksh, Sarah E. Pape, Andre Strydom, Martin C. Gulliford, Li F. Chan, GO-DS21 Consortium; for the GO-DS21 Consortium, Diabetes and Obesity in Down Syndrome Across the Lifespan: A Retrospective Cohort Study Using U.K. Electronic Health Records. Diabetes Care 2022; dc220482. https://doi.org/10.2337/dc22-0482
Dr.Niharika Harsha B (BDS,MDS) completed her BDS from Govt Dental College, Hyderabad and MDS from Dr.NTR University of health sciences(Now Kaloji Rao University). She has 4 years of private dental practice and worked for 2 years as Consultant Oral Radiologist at a Dental Imaging Centre in Hyderabad. She worked as Research Assistant and scientific writer in the development of Oral Anti cancer screening device with her seniors. She has a deep intriguing wish in writing highly engaging, captivating and informative medical content for a wider audience. She can be contacted at editorial@medicaldialogues.in.
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